About granisetron
5-HT3 serotonin receptor antagonist
Used for
- Prevention of nausea and vomiting caused by chemotherapy
Usual adult dose
Apply one patch to clean, dry skin 24–48 hours before chemotherapy; keep on for up to seven days.
Common side effects
- Constipation
- Headache
- Skin redness, itching, or rash
Important warnings
- Use only for chemotherapy-related nausea and vomiting.
- May cause serotonin syndrome, especially with other serotonergic medicines.
- Can affect heart rhythm; risk is higher with certain conditions or medicines.
- Sunlight may reduce patch effectiveness; cover the application site.
Pregnancy
Human pregnancy information is limited; use only when clearly needed.
Breastfeeding
It is unknown whether granisetron passes into breast milk; breastfeeding safety is not established.
Interactions
- Serotonergic medicines may increase serotonin syndrome risk.
- Medicines that prolong the QT interval may increase abnormal heart rhythm risk.
- Strong CYP3A inhibitors or inducers may alter granisetron exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.