About granisetron
Serotonin 5-HT3 receptor antagonist
Used for
- Prevents nausea and vomiting from chemotherapy, especially when treatment lasts several days.
Usual adult dose
Apply one patch 24–48 hours before chemotherapy; leave in place for up to 7 days.
Common side effects
- Constipation
- Headache
- Skin redness, itching, or irritation
Important warnings
- Can affect heart rhythm, including QT prolongation.
- Seek urgent care for severe allergic reaction or signs of serotonin syndrome.
- May mask symptoms of bowel obstruction.
- Do not cut the patch; remove before MRI or defibrillation.
Pregnancy
Human pregnancy data are limited; use only when clearly needed.
Breastfeeding
It is unknown whether granisetron passes into breast milk; breastfeeding safety is not established.
Interactions
- Other medicines that prolong QT can increase heart-rhythm risk.
- Serotonergic medicines may increase serotonin syndrome risk.
- Medicines affecting CYP3A4 may alter granisetron levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.