About piroxicam
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Relief of pain and inflammation in osteoarthritis and rheumatoid arthritis
Usual adult dose
Usually 20 mg once daily; rectal use depends on the product’s approved directions.
Common side effects
- Stomach pain, indigestion, nausea, or diarrhea
- Dizziness or headache
- Fluid retention and raised blood pressure
- Stomach ulcer or bleeding
Important warnings
- Can cause serious stomach bleeding, ulcers, or bowel perforation.
- May increase heart attack and stroke risk, especially with prolonged use.
- Avoid with other NSAIDs; use caution with kidney, liver, or heart disease.
- Rectal use may irritate or injure the rectum.
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid from 30 weeks because of fetal risks.
Breastfeeding
Generally avoid; information is limited and safer alternatives may be preferred.
Interactions
- Blood thinners and antiplatelet medicines increase bleeding risk.
- Other NSAIDs, including ibuprofen and naproxen, increase side effects.
- Some blood pressure medicines and diuretics may work less well.
- Lithium and methotrexate levels may rise.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.