About mycophenolate mofetil
Immunosuppressant; antimetabolite
Used for
- Prevents organ rejection after kidney, heart, or liver transplant
Usual adult dose
Usually 1 g twice daily after kidney transplant; 1.5 g twice daily after heart or liver transplant.
Usual dose in children
Kidney transplant: ages 3 months–18 years, usually 600 mg/m² twice daily, maximum 1 g twice daily.
Common side effects
- Diarrhea, nausea, vomiting, or stomach pain
- Low blood cell counts and increased infection risk
- Serious infections, including viral infections
- Increased risk of certain cancers
Important warnings
- Can cause miscarriage and birth defects; pregnancy testing and effective contraception are required.
- Do not use with azathioprine; blood counts and infections need monitoring.
- Capsules must be swallowed whole; avoid contact with broken or leaking capsules.
- Do not stop or change treatment without the transplant team’s direction.
Pregnancy
Can cause pregnancy loss and severe birth defects; avoid during pregnancy unless no suitable alternative exists.
Breastfeeding
Whether mycophenolate passes into breast milk is unknown; breastfeeding is generally not recommended during treatment.
Interactions
- Antacids containing magnesium or aluminum can reduce absorption.
- Cholestyramine and some phosphate binders can reduce exposure.
- Acyclovir or ganciclovir may increase drug levels or blood-related side effects.
- Live vaccines may be unsafe or less effective during treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.