About mycophenolate mofetil
Immunosuppressant antimetabolite
Used for
- Prevents organ rejection after kidney, heart, or liver transplantation.
Usual adult dose
Usually 1 g intravenously every 12 hours after kidney transplant; 1.5 g every 12 hours after heart or liver transplant.
Usual dose in children
For kidney transplant, usually 600 mg/m² intravenously every 12 hours; maximum 1 g per dose.
Common side effects
- Diarrhea, nausea, vomiting, or abdominal pain
- Low blood cell counts and increased infection risk
- High blood pressure or swelling
- Serious infections or certain cancers
Important warnings
- Increases risk of serious infections and some cancers.
- Can cause severe birth defects or pregnancy loss.
- Blood counts and signs of infection require monitoring.
- Use only under specialist supervision after transplantation.
Pregnancy
Can cause miscarriage and severe birth defects. Avoid during pregnancy unless no suitable alternative; effective contraception is required.
Breastfeeding
Breastfeeding is generally not recommended during treatment because of potential serious infant harm.
Interactions
- Antacids containing magnesium or aluminum can reduce absorption.
- Acyclovir and ganciclovir may increase drug levels or blood-cell toxicity.
- Cholestyramine and some phosphate binders can reduce drug absorption.
- Live vaccines may cause infection or work less effectively.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.