About enoxaparin sodium
Low-molecular-weight heparin anticoagulant
Used for
- Prevents blood clots after surgery or during reduced mobility
- Treats deep vein thrombosis and pulmonary embolism
- Treats certain heart attacks and unstable angina
- Prevents clotting during haemodialysis
Usual adult dose
Varies by use and kidney function. Common regimens are 40 mg under the skin daily for prevention, or 1 mg/kg every 12 hours for treatment.
Usual dose in children
Specialist dosing by weight is used for children; the dose depends on age and condition.
Common side effects
- Bleeding or bruising
- Low platelet count
- Anaemia
- Injection-site pain or irritation
Important warnings
- Serious bleeding can occur; risk rises with some medicines or procedures.
- Dose adjustment may be needed with severe kidney impairment.
- Rarely, spinal or epidural bleeding can cause lasting paralysis.
- Do not use with a history of immune-mediated heparin-induced thrombocytopenia unless directed by a specialist.
Pregnancy
May be used when needed during pregnancy; specialist assessment is important. It does not cross the placenta.
Breastfeeding
Generally considered compatible with breastfeeding because transfer into milk is unlikely and absorption by the infant is poor.
Interactions
- Other anticoagulants or antiplatelet medicines increase bleeding risk.
- NSAIDs, including ibuprofen, can increase bleeding risk.
- Medicines that affect platelets may increase bleeding risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.