About co amoxiclav
Penicillin antibiotic with beta-lactamase inhibitor
Used for
- Bacterial infections of the sinuses, ears, chest, skin, and urinary tract
- Dental infections
Usual adult dose
Usually 500/125 mg three times daily or 875/125 mg twice daily, depending on infection and local guidance.
Usual dose in children
Children’s doses are based on weight and infection; tablets are unsuitable for many young children.
Common side effects
- Diarrhoea, nausea, or vomiting
- Thrush
- Skin rash
- Rarely, severe allergic reaction or liver problems
Important warnings
- Do not use with a serious penicillin allergy.
- Previous liver problems caused by co-amoxiclav are a reason to avoid it.
- Seek urgent help for breathing difficulty, facial swelling, or a severe blistering rash.
- Use only for bacterial infections; complete the prescribed course.
Pregnancy
Can be used when needed; a clinician should weigh benefits and risks.
Breastfeeding
Generally compatible; monitor the infant for diarrhoea, rash, or thrush.
Interactions
- Warfarin and similar anticoagulants may need extra monitoring.
- Methotrexate may cause increased toxicity.
- Allopurinol may increase the chance of skin rash.
- Probenecid can increase amoxicillin levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.