About co amoxiclav
Penicillin antibiotic with beta-lactamase inhibitor
Used for
- Treats susceptible bacterial infections, including respiratory, urinary, skin, and dental infections.
- Used for some severe infections requiring injection or infusion.
Usual adult dose
Usually 1.2 g by injection or infusion every 8 hours; some severe infections require every 6 hours. Adjust for kidney function.
Usual dose in children
Children under 40 kg: usually 25/5 mg/kg every 8 hours; some severe infections require every 6 hours. Dosing depends on age, weight, and kidney function.
Common side effects
- Diarrhea, nausea, or vomiting
- Rash or itching
- Injection-site pain or inflammation
- Rarely, liver problems or severe allergic reactions
Important warnings
- Do not use with serious penicillin allergy or previous co-amoxiclav-related jaundice.
- Seek urgent care for breathing difficulty, facial swelling, or a severe blistering rash.
- Kidney impairment may require dose adjustment.
- Antibiotics do not treat viral infections.
Pregnancy
May be used when clinically needed; a clinician should assess benefits and risks.
Breastfeeding
Generally compatible; monitor the infant for diarrhea, rash, or oral thrush.
Interactions
- Warfarin and related anticoagulants: may alter clotting tests.
- Methotrexate: may increase methotrexate effects or toxicity.
- Allopurinol: may increase the chance of skin rash.
- Probenecid: may increase and prolong amoxicillin levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.