About domperidone
Dopamine antagonist; antiemetic
Used for
- Relief of nausea and vomiting
- Treatment of delayed stomach emptying in some settings
Usual adult dose
Usually 10 mg up to three times daily, before meals; use the lowest effective dose for the shortest time.
Common side effects
- Dry mouth
- Headache
- Abdominal cramps or diarrhea
- Raised prolactin, causing breast symptoms
Important warnings
- Can cause serious abnormal heart rhythms, especially with higher doses or prolonged use.
- Avoid with certain heart conditions, significant liver disease, or medicines that affect heart rhythm.
- Use is restricted in many countries; follow local product guidance.
Pregnancy
Generally avoided unless a clinician considers it necessary; pregnancy safety information is limited.
Breastfeeding
Passes into breast milk in small amounts; use only if a clinician considers it appropriate.
Interactions
- Some antibiotics and antifungals can increase heart-rhythm risk.
- Avoid combining with medicines that prolong the QT interval.
- Strong CYP3A4 inhibitors can raise domperidone levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.