About prochlorperazine
Phenothiazine antiemetic and antipsychotic
Used for
- Severe nausea and vomiting
- Short-term treatment of schizophrenia and other psychotic disorders
Usual adult dose
Nausea and vomiting: usually 5–10 mg by injection, repeated as needed under medical supervision. Psychosis: dosing is individualized.
Usual dose in children
For nausea and vomiting, doses are age- and weight-based and require medical supervision; injection use is generally avoided in young children.
Common side effects
- Drowsiness, dizziness, or blurred vision
- Low blood pressure, especially after injection
- Movement problems, including muscle stiffness or restlessness
- Dry mouth or constipation
Important warnings
- May cause severe sleepiness; avoid alcohol and use caution with driving.
- Seek urgent care for fever with severe stiffness, confusion, or abnormal movements.
- Use cautiously with heart rhythm problems, low blood pressure, or seizure disorders.
- Not recommended for children under 2 years or weighing under 10 kg.
Pregnancy
Use only when clinically necessary after weighing benefits and risks; exposure near delivery may affect the newborn.
Breastfeeding
May cause infant drowsiness and can reduce milk supply; clinical advice is needed before use.
Interactions
- Alcohol, opioids, and sedatives increase drowsiness.
- Medicines that prolong the QT interval may increase abnormal heart rhythm risk.
- Levodopa and dopamine agonists may work less effectively.
- Blood-pressure-lowering medicines may increase dizziness or fainting.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.