About baricitinib
Janus kinase (JAK) inhibitor
Used for
- Rheumatoid arthritis
- Severe alopecia areata
- Atopic dermatitis
- Hospitalized adults with COVID-19 requiring oxygen
Usual adult dose
Rheumatoid arthritis, alopecia areata, or dermatitis: usually 2 mg once daily. COVID-19: 4 mg once daily, up to 14 days.
Usual dose in children
Ages 2 years and older with juvenile idiopathic arthritis: dose depends on weight, usually once daily.
Common side effects
- Upper respiratory infections
- Nausea
- Headache
- Raised cholesterol or liver enzymes
Important warnings
- May cause serious infections, including tuberculosis and shingles.
- Can increase risks of blood clots, major heart events, and certain cancers.
- May lower blood cell counts; monitoring is required.
- Avoid live vaccines; screen for tuberculosis and hepatitis before treatment.
Pregnancy
May cause fetal harm based on animal studies; human pregnancy information is limited.
Breastfeeding
Avoid breastfeeding during treatment and for four days after the last dose.
Interactions
- Probenecid increases baricitinib levels and may require dose adjustment.
- Other strong immunosuppressants can increase infection risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.