About baricitinib
Janus kinase (JAK) inhibitor
Used for
- Rheumatoid arthritis
- Atopic dermatitis
- Alopecia areata
- Hospitalized COVID-19 in selected patients
Usual adult dose
Usually 2 mg once daily for rheumatoid arthritis or atopic dermatitis; other conditions and local approvals may differ.
Usual dose in children
For juvenile idiopathic arthritis, usually 4 mg once daily for children weighing at least 30 kg; not for younger or lighter children.
Common side effects
- Upper respiratory infections
- Nausea
- Headache
- Raised cholesterol or liver enzymes
Important warnings
- Can increase risk of serious infections, including tuberculosis and shingles.
- May increase risk of blood clots, heart problems, and certain cancers.
- Blood counts, liver enzymes, and cholesterol may need monitoring.
- Avoid live vaccines during treatment.
Pregnancy
May harm an unborn baby; avoid use during pregnancy. Effective contraception is recommended during treatment and for one week afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for one week after the last dose.
Interactions
- Other potent immunosuppressants may increase infection risk.
- Strong OAT3 inhibitors, such as probenecid, can raise baricitinib levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.