About dinoprostone
Prostaglandin E2 uterotonic
Used for
- Induces labour by softening and opening the cervix.
Usual adult dose
Usually 3 mg inserted high in the vagina; may repeat once after 6–8 hours if needed.
Common side effects
- Nausea or vomiting
- Diarrhoea
- Fever or chills
- Uterine contractions that are too strong or frequent
Important warnings
- Used only under hospital supervision with monitoring of contractions and the baby’s heart rate.
- Avoid with a prior caesarean or major uterine surgery, or when vaginal birth is unsuitable.
- Risk of uterine rupture, especially with excessive contractions or uterine scarring.
- Do not use with other labour-inducing medicines unless carefully timed and supervised.
Pregnancy
Used to induce labour at or near term under medical supervision; not for routine use earlier in pregnancy.
Breastfeeding
Not generally relevant during labour induction; ask the treating team about breastfeeding after birth.
Interactions
- Oxytocin and other medicines that stimulate the uterus can increase contraction-related risks.
- Other prostaglandins may increase uterine effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.