About dinoprostone
Prostaglandin E2 uterotonic
Used for
- Induction of labour in selected pregnancies under specialist supervision.
Usual adult dose
For intravenous labour induction, protocols vary; a commonly used regimen starts at 0.5–1 microgram/minute, adjusted by response.
Common side effects
- Nausea, vomiting, diarrhoea
- Fever, flushing, headache
- Excessive uterine contractions
- Changes in fetal heart rate
Important warnings
- Use only in a hospital with continuous maternal and fetal monitoring.
- Excessive contractions can cause fetal distress or uterine rupture.
- Avoid or use extreme caution with conditions where vaginal birth is unsafe.
- Concentrate requires correct dilution; route and dose depend on the specific product.
Pregnancy
Used to induce labour at term or when medically indicated; requires specialist supervision.
Breastfeeding
Not usually relevant during labour induction; seek product-specific guidance if breastfeeding after delivery.
Interactions
- Oxytocin and other uterotonic medicines can increase excessive contractions.
- Other prostaglandins may increase uterine effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.