About progesterone
Natural progesterone hormone
Used for
- Luteal support during assisted reproduction
- Treatment of premenstrual syndrome
- Treatment of postpartum depression in some countries
Usual adult dose
Assisted reproduction: commonly 400 mg vaginally twice daily, according to protocol. Other uses vary by country and product guidance.
Common side effects
- Sleepiness or dizziness
- Headache
- Breast tenderness
- Vaginal irritation or discharge
Important warnings
- May cause drowsiness; avoid driving if affected.
- Seek urgent care for chest pain, breathlessness, or one-sided leg swelling.
- Use caution with unexplained vaginal bleeding or severe liver disease.
- Product instructions and approved uses vary by country.
Pregnancy
Used in pregnancy for specific indications, including fertility treatment; use depends on clinical guidance.
Breastfeeding
Progesterone enters breast milk in small amounts; clinical effects on nursing infants are not well established.
Interactions
- Enzyme-inducing medicines, such as carbamazepine or rifampicin, may reduce progesterone effects.
- Some vaginal products may alter absorption; check product-specific instructions.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.