About progesterone
Natural progesterone hormone
Used for
- Luteal support during assisted reproduction, such as IVF.
- Treatment of premenstrual syndrome in some countries.
Usual adult dose
For IVF luteal support: 400 mg vaginally twice daily, as prescribed by a specialist.
Common side effects
- Vaginal irritation, discharge, or discomfort.
- Sleepiness, dizziness, or headache.
- Breast tenderness or abdominal discomfort.
- Mood changes.
Important warnings
- May cause sleepiness or dizziness; caution with activities requiring alertness.
- Seek urgent care for signs of a blood clot, stroke, or severe allergic reaction.
- Not a contraceptive; does not reliably prevent pregnancy.
- Use vaginally only; product-specific directions vary by indication and country.
Pregnancy
Used to support pregnancy in assisted reproduction; use only for a prescribed indication.
Breastfeeding
Progesterone enters breast milk in small amounts; use depends on clinical circumstances.
Interactions
- Enzyme-inducing medicines, including rifampicin and some seizure medicines, may reduce progesterone effects.
- Some antifungal medicines and other enzyme inhibitors may alter progesterone levels.
- Other vaginal products may affect absorption; check product instructions.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.