About deferiprone
Iron-chelating agent
Used for
- Treats iron overload from repeated blood transfusions in thalassemia and other conditions.
- May be used when other chelation treatments are unsuitable or insufficient.
Usual adult dose
Usually 75 mg/kg daily, divided into three doses; some adults may use 100 mg/kg daily. Modified-release dosing differs; follow the product label.
Usual dose in children
Usually 75 mg/kg daily, divided into three doses; specialist-supervised dosing may differ.
Common side effects
- Nausea, abdominal pain, vomiting, or diarrhea
- Joint pain
- Low white blood cells, including severe neutropenia
- Increased liver enzymes
Important warnings
- Can cause severe neutropenia or agranulocytosis, increasing risk of serious infection.
- Regular blood tests are required to monitor white blood cells and liver function.
- Report fever, sore throat, or other infection symptoms promptly.
- Avoid taking iron supplements unless specifically directed.
Pregnancy
May harm an unborn baby. Avoid during pregnancy; effective contraception is needed during treatment and for six months afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for two weeks after the final dose.
Interactions
- Iron supplements can reduce deferiprone absorption; separate doses as directed.
- Avoid medicines associated with neutropenia or agranulocytosis unless closely supervised.
- Aluminum-containing antacids may affect absorption; ask a clinician about dose separation.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.