About deferiprone
Iron-chelating agent
Used for
- Treats iron overload in people with thalassemia when other chelation treatment is unsuitable or inadequate.
Usual adult dose
Usually 25 mg/kg by mouth three times daily; specialist-guided dose may increase, up to 33 mg/kg three times daily.
Usual dose in children
For children aged 8 years and older: usually 25 mg/kg by mouth three times daily; specialist-guided dosing may vary.
Common side effects
- Nausea, vomiting, abdominal pain, or diarrhea
- Joint pain
- Increased liver enzymes
- Low neutrophil count or severe infection
Important warnings
- Can cause life-threatening neutropenia or agranulocytosis; regular blood-count monitoring is essential.
- Report fever, sore throat, or infection symptoms promptly; treatment may need to stop.
- Liver tests and zinc levels require monitoring.
- Avoid taking with iron supplements or aluminium-containing antacids unless directed.
Pregnancy
May harm an unborn baby. Avoid during pregnancy; effective contraception is required during treatment and for six months afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for two weeks after the last dose.
Interactions
- Other medicines that can lower neutrophils may increase infection risk.
- Zinc supplements may interact; zinc levels require monitoring.
- Iron supplements and aluminium-containing antacids can interfere with treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.