About carglumic acid
Urea-cycle disorder treatment
Used for
- Treats high ammonia from N-acetylglutamate synthase deficiency.
- Treats high ammonia in certain organic acid disorders.
Usual adult dose
Usually 100–250 mg/kg daily, divided into 2–4 doses; adjusted to ammonia levels.
Usual dose in children
Usually 100–250 mg/kg daily, divided into 2–4 doses; adjusted to ammonia levels.
Common side effects
- Vomiting
- Fever
- Diarrhea
- Reduced appetite
Important warnings
- Requires specialist supervision and blood ammonia monitoring.
- Dose is individualized; do not stop abruptly without medical guidance.
- Disperse tablets in water as directed; do not swallow whole.
Pregnancy
Use only when clearly needed; human pregnancy data are limited.
Breastfeeding
Unknown whether it passes into breast milk; use under specialist guidance.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.