About sevelamer carbonate
Phosphate-binding medicine
Used for
- Lowers high blood phosphate in people with chronic kidney disease.
- Used in dialysis and, in some cases, advanced kidney disease without dialysis.
Usual adult dose
Usually 800–1,600 mg with each meal; dose is adjusted to blood phosphate levels.
Usual dose in children
For children with chronic kidney disease, doses are individualized by body surface area and blood phosphate levels.
Common side effects
- Nausea or vomiting
- Diarrhea, constipation, or abdominal pain
- Indigestion or gas
Important warnings
- Take with meals; swallowing tablets whole is generally recommended.
- May cause bowel blockage, bleeding, ulcers, or rarely bowel perforation.
- Can reduce absorption of some medicines and fat-soluble vitamins.
- Use caution with swallowing problems or severe gastrointestinal disease.
Pregnancy
There are limited pregnancy data; absorption into the body is minimal, but use should be based on clinical need.
Breastfeeding
There are limited data; absorption into the body is minimal, so exposure through breast milk is expected to be low.
Interactions
- Take ciprofloxacin at least two hours before or six hours after sevelamer.
- Separate levothyroxine by at least four hours; monitor thyroid function.
- Some medicines, including mycophenolate, may need monitoring or separation.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.