About sevelamer carbonate
Phosphate-binding polymer
Used for
- Controls high blood phosphate in adults and children with chronic kidney disease on dialysis.
- Controls high blood phosphate in adults with chronic kidney disease not on dialysis.
Usual adult dose
Usually 800–1,600 mg with each meal; adjust according to blood phosphate. Take with food.
Usual dose in children
For children aged 6 years and older on dialysis, dose is individualized by body surface area and blood phosphate; take with meals.
Common side effects
- Nausea or vomiting
- Constipation or diarrhea
- Abdominal pain or indigestion
- Gas
Important warnings
- Can cause severe constipation, bowel blockage, or perforation; risk is higher with bowel disorders.
- May lower vitamins A, D, E, and K; monitor as clinically appropriate.
- Not absorbed to a meaningful extent; use in pregnancy only when clearly needed.
- Mix the powder as directed; do not swallow it dry.
Pregnancy
Limited human data; systemic absorption is minimal. Use only when clearly needed, with clinical monitoring.
Breastfeeding
Systemic absorption is minimal, so exposure through breast milk is unlikely; clinical data are limited.
Interactions
- May reduce absorption of levothyroxine; separate doses and monitor thyroid function.
- May reduce absorption of ciprofloxacin; separate administration by at least two hours.
- May reduce absorption of mycophenolate; monitor transplant patients closely.
- Separate other oral medicines when reduced absorption could matter; timing depends on the medicine.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.