About ketoprofen
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Relief of pain and inflammation, including arthritis and musculoskeletal conditions
- Short-term treatment of acute pain, such as menstrual pain
Usual adult dose
Commonly 100 mg rectally once or twice daily; maximum 200 mg daily.
Common side effects
- Indigestion, nausea, or abdominal pain
- Diarrhea or constipation
- Dizziness or headache
- Rectal irritation or discomfort
Important warnings
- Can cause stomach ulcers, bleeding, or perforation.
- May increase risks of heart attack and stroke, especially with prolonged use.
- Avoid with active stomach ulcers, severe heart failure, or previous NSAID allergy.
- Use the lowest effective dose for the shortest time.
Pregnancy
Avoid from 20 weeks unless medically necessary; do not use from 30 weeks onward. Earlier use requires medical guidance.
Breastfeeding
Generally not recommended because information is limited; seek professional guidance about alternatives.
Interactions
- Other NSAIDs or aspirin increase bleeding and stomach risks.
- Blood thinners, such as warfarin, increase bleeding risk.
- ACE inhibitors, ARBs, or diuretics may affect kidney function.
- Lithium or methotrexate levels may rise.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.