About ketoprofen
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Relief of pain and inflammation in arthritis
- Short-term treatment of musculoskeletal pain
- Period pain
Usual adult dose
Usually 50–100 mg two or three times daily, with the lowest effective dose for the shortest time.
Common side effects
- Indigestion, stomach pain, nausea, or diarrhoea
- Headache or dizziness
- Stomach ulcer or bleeding
- Fluid retention or raised blood pressure
Important warnings
- Can cause serious stomach bleeding, ulcers, or perforation.
- May increase heart attack or stroke risk, especially with higher doses or prolonged use.
- Avoid with active stomach ulcers, severe heart failure, or prior NSAID allergy.
- Use caution with kidney, liver, or heart disease; older adults face higher risks.
Pregnancy
Avoid from 20 weeks unless medically necessary; contraindicated in the last trimester.
Breastfeeding
Generally not recommended; seek clinical advice about alternatives.
Interactions
- Other NSAIDs or aspirin increase bleeding and stomach risks.
- Blood thinners, corticosteroids, and some antidepressants increase bleeding risk.
- ACE inhibitors, ARBs, diuretics, and lithium may interact.
- Methotrexate levels or toxicity may increase.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.