About paliperidone
Long-acting atypical antipsychotic
Used for
- Maintenance treatment of schizophrenia in adults after stabilization with monthly or three-monthly paliperidone injections
Usual adult dose
Given by a healthcare professional every six months; dose depends on the previous paliperidone injection regimen.
Common side effects
- Injection-site reactions
- Weight gain
- Sleepiness or restlessness
- Movement problems, including stiffness or tremor
Important warnings
- Can increase blood sugar, cholesterol, and weight
- May cause tardive dyskinesia or neuroleptic malignant syndrome
- Can cause dizziness from low blood pressure
- Not approved for children
Pregnancy
May cause movement or withdrawal symptoms in newborns after exposure late in pregnancy; risks and benefits require clinical assessment.
Breastfeeding
Paliperidone passes into breast milk; effects on a nursing infant are uncertain.
Interactions
- Other medicines that prolong the QT interval may increase abnormal heart rhythm risk
- Carbamazepine can lower paliperidone levels
- Sedatives and alcohol can increase sleepiness
- Levodopa and dopamine agonists may work less effectively
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.