About flucloxacillin
Penicillin antibiotic
Used for
- Treats serious infections caused by susceptible bacteria, including skin, bone, and bloodstream infections.
- Used when flucloxacillin injections are needed, such as when oral treatment is unsuitable.
Usual adult dose
Often 1–2 g intravenously every 6 hours; dose depends on infection and clinical circumstances.
Usual dose in children
Typically 12.5–25 mg/kg intravenously every 6 hours; severe infections may require higher doses.
Common side effects
- Nausea, vomiting, or diarrhoea
- Injection-site pain or inflammation
- Rash or allergic reactions
- Rarely, liver inflammation or jaundice
Important warnings
- Do not use with a history of serious penicillin allergy.
- Seek urgent care for breathing difficulty, facial swelling, or a severe rash.
- Use carefully with liver or kidney problems; prolonged treatment may need monitoring.
- Antibiotics do not treat viral infections.
Pregnancy
May be used during pregnancy when clinically needed; available safety information is generally reassuring.
Breastfeeding
Usually compatible with breastfeeding; monitor the infant for diarrhoea, rash, or thrush.
Interactions
- Probenecid may increase flucloxacillin levels.
- Warfarin effects may change; monitoring may be needed.
- Methotrexate toxicity risk may increase.
- Other medicines affecting the liver may warrant monitoring.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.