About desmopressin acetate
Antidiuretic hormone analogue
Used for
- Central diabetes insipidus
- Prevention or treatment of bleeding in selected clotting disorders
- Control of excessive bleeding after surgery
Usual adult dose
For central diabetes insipidus, dosing is individualized, commonly 1–4 mcg by injection once or twice daily.
Usual dose in children
For central diabetes insipidus, dosing is individualized by a specialist, commonly 0.1–1 mcg by injection once or twice daily.
Common side effects
- Headache
- Nausea
- Flushing
- Fluid retention and low blood sodium
Important warnings
- Can cause dangerously low blood sodium, seizures, or coma.
- Fluid intake may need restriction; monitoring depends on use and patient risk.
- Not suitable for some heart, kidney, or electrolyte conditions.
- Bleeding-disorder uses require specialist assessment and appropriate monitoring.
Pregnancy
Use only when clinically needed; pregnancy data are limited, and monitoring may be required.
Breastfeeding
Small amounts may enter milk; effects on the infant are considered unlikely, but data are limited.
Interactions
- Medicines that increase low-sodium risk, including some antidepressants and carbamazepine
- NSAIDs, which may increase fluid retention
- Lithium, which may reduce desmopressin’s antidiuretic effect
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.