About tobramycin sulfate
Aminoglycoside antibiotic
Used for
- Treats serious infections caused by susceptible bacteria, including some bloodstream, lung, urinary, and bone infections.
Usual adult dose
Usually 3–5 mg/kg per day intravenously or intramuscularly, divided into doses; adjusted for kidney function and infection.
Usual dose in children
Usually 6–7.5 mg/kg per day intravenously or intramuscularly, divided into doses; adjusted for age, kidney function, and infection.
Common side effects
- Kidney damage
- Hearing or balance damage, sometimes permanent
- Nausea
- Injection-site pain
Important warnings
- Requires monitoring of kidney function and, often, blood drug levels.
- Risk of hearing damage increases with prolonged treatment or impaired kidney function.
- Use cautiously with other medicines that can harm the kidneys or hearing.
- Can cause muscle weakness or breathing problems, especially with neuromuscular disorders.
Pregnancy
May harm the developing baby’s hearing; use only when clearly needed and benefits outweigh risks.
Breastfeeding
Small amounts may enter breast milk; infant absorption is expected to be low, but monitor for diarrhea or thrush.
Interactions
- Other kidney- or hearing-damaging medicines, such as vancomycin or loop diuretics
- Neuromuscular blockers and some anesthetics
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.