About glucagon
Glucose-raising hormone
Used for
- Emergency treatment of severe low blood sugar in adults and children with diabetes.
Usual adult dose
One 3 mg spray into one nostril once; may repeat after 15 minutes using a new device if needed.
Usual dose in children
One 3 mg spray into one nostril once; may repeat after 15 minutes using a new device if needed.
Common side effects
- Nausea or vomiting
- Headache
- Watery or irritated eyes
- Runny nose or nasal discomfort
Important warnings
- Call emergency services after giving it; give food or drink containing sugar when the person can swallow safely.
- If the person does not respond after 15 minutes, another dose may be given while awaiting emergency help.
- May be less effective after prolonged fasting, chronic low blood sugar, or adrenal insufficiency.
- Not for people with pheochromocytoma or insulinoma; allergy to glucagon is also a concern.
Pregnancy
Use for severe low blood sugar when needed; untreated hypoglycemia can endanger the pregnant person and fetus.
Breastfeeding
Glucagon is not expected to harm a breastfed infant; breastfeeding can resume once the person is alert and able.
Interactions
- Beta-blockers may increase heart rate and blood pressure after glucagon.
- Indomethacin may reduce glucagon’s blood-sugar-raising effect.
- Warfarin effects may be increased.
- Anticholinergic medicines may increase gastrointestinal side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.