About pergolide mesilate
Dopamine receptor agonist
Used for
- Previously used to treat Parkinson’s disease.
- Veterinary formulations are used for pituitary-related disease in horses.
Usual adult dose
Parkinson’s disease: formerly started at 0.05 mg daily, then increased gradually; no longer recommended in many countries.
Common side effects
- Nausea, vomiting, and constipation
- Dizziness, fainting, and low blood pressure
- Hallucinations, confusion, or sleepiness
- Heart-valve disease and scarring around organs
Important warnings
- Withdrawn or restricted in many countries because of heart-valve damage.
- Can cause sudden sleepiness, fainting, and compulsive behaviors.
- Do not stop abruptly without medical supervision.
- Use veterinary products only under a veterinarian’s direction.
Pregnancy
Human pregnancy safety is not established; use only when clearly necessary under specialist care.
Breastfeeding
May suppress milk production; breastfeeding safety is not established.
Interactions
- Other dopamine-blocking medicines may reduce its effect.
- Blood-pressure-lowering medicines may increase dizziness or fainting.
- Alcohol and sedatives may worsen sleepiness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.