About baloxavir marboxil
Influenza antiviral, cap-dependent endonuclease inhibitor
Used for
- Treatment of uncomplicated influenza in people aged 5 years and older, started within 48 hours of symptoms.
- Prevention of influenza after exposure in people aged 5 years and older.
Usual adult dose
Single dose by mouth within 48 hours: 40 mg if under 80 kg; 80 mg if 80 kg or more.
Usual dose in children
Age 5 years and older: single dose by mouth within 48 hours. Under 20 kg: 2 mg/kg; 20 to under 80 kg: 40 mg; 80 kg or more: 80 mg.
Common side effects
Important warnings
- Not recommended for severe or complicated influenza or hospitalized patients.
- Avoid taking with dairy products, calcium-fortified drinks, antacids, or supplements containing polyvalent cations.
- Rare serious allergic reactions, including swelling and severe skin reactions, have been reported.
Pregnancy
Human pregnancy data are limited; use only when the potential benefit justifies possible risk.
Breastfeeding
It is unknown whether baloxavir passes into breast milk; human data are limited.
Interactions
- Calcium, iron, magnesium, zinc, aluminum, and other polyvalent cations may reduce absorption.
- Avoid use with dairy products and calcium-fortified beverages.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.