About sodium aminosalicylate
Aminosalicylate antituberculosis medicine
Used for
- Used with other medicines to treat tuberculosis, especially drug-resistant tuberculosis.
Usual adult dose
Usually 8–12 g daily in divided doses, with other tuberculosis medicines.
Usual dose in children
Usually 200–300 mg/kg daily in divided doses; maximum 10 g daily.
Common side effects
- Nausea, vomiting, diarrhea, or abdominal discomfort
- Rash, itching, or fever
- Low thyroid hormone with prolonged treatment
- Rarely, liver inflammation or blood disorders
Important warnings
- Must be used with other tuberculosis medicines under specialist supervision.
- Seek urgent assessment for severe rash, jaundice, unusual bruising, or breathing difficulty.
- Use caution with kidney or liver disease.
- Treatment may require thyroid, liver, kidney, and blood monitoring.
Pregnancy
May be used when needed for tuberculosis; treatment choice should be specialist-led because evidence is limited.
Breastfeeding
Small amounts may enter breast milk; use requires clinician assessment, especially for newborns.
Interactions
- May reduce vitamin B12 absorption with long-term use.
- Can affect absorption of digoxin and other medicines; timing may need adjustment.
- May increase effects of warfarin and related anticoagulants.
- Combining with other liver-affecting medicines may increase liver injury risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.