About cariprazine hcl
Atypical antipsychotic
Used for
- Schizophrenia in adults
- Manic or mixed episodes of bipolar I disorder in adults
- Depressive episodes of bipolar I disorder in adults
Usual adult dose
Usually 1.5–6 mg once daily for schizophrenia or mania; 1.5–3 mg once daily for bipolar depression.
Common side effects
- Restlessness or difficulty sitting still
- Insomnia
- Nausea
- Movement problems, including tremor or stiffness
Important warnings
- May increase risk of death in older adults with dementia-related psychosis.
- Can cause tardive dyskinesia, a potentially persistent movement disorder.
- May cause neuroleptic malignant syndrome, high blood sugar, or low blood pressure.
- Effects and side effects can emerge or persist for weeks after dose changes.
Pregnancy
May cause movement symptoms in newborns after exposure late in pregnancy; discuss risks with a clinician.
Breastfeeding
Breastfeeding is not recommended during treatment or for 10 weeks after the last dose.
Interactions
- Strong CYP3A4 inhibitors can raise cariprazine levels; dosage adjustment is required.
- Strong CYP3A4 inducers may reduce effectiveness; avoid combination.
- Other medicines causing sleepiness or low blood pressure may increase these effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.