About nonacog beta pegol
Long-acting recombinant factor IX
Used for
- Prevention and treatment of bleeding in haemophilia B
- Bleeding control during and after surgery in haemophilia B
Usual adult dose
Prevention: usually 40 IU/kg once weekly. Bleeding and surgery doses depend on severity and clinical response.
Usual dose in children
For children aged 12 years and older: usually 40 IU/kg once weekly for prevention. Not recommended under 12 years.
Common side effects
- Injection-site reactions
- Nausea
- Itching or rash
- Development of factor IX inhibitors or allergic reactions
Important warnings
- Seek urgent care for symptoms of a severe allergic reaction.
- Inhibitors can make treatment less effective and increase bleeding risk.
- Use caution with kidney or urinary tract bleeding; blood clots have been reported.
- Dosing should be guided by a haemophilia specialist and factor IX monitoring.
Pregnancy
Limited information; use during pregnancy only when clearly needed, under specialist supervision.
Breastfeeding
Unknown whether it passes into breast milk; use only when clinically necessary.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.