About certolizumab pegol in one ml excipients sodium acetate + sodium chloride + water for injection
TNF inhibitor biologic
Used for
- Rheumatoid arthritis
- Psoriatic arthritis
- Axial spondyloarthritis, including ankylosing spondylitis
- Crohn’s disease and plaque psoriasis in some countries
Usual adult dose
Usually 400 mg under the skin at weeks 0, 2, and 4, then 200 mg every two weeks or 400 mg every four weeks; schedules vary by condition.
Common side effects
- Upper respiratory infections
- Injection-site pain or reactions
- Headache
- Rash
Important warnings
- May cause serious infections, including tuberculosis; screening is needed before treatment.
- Avoid live vaccines during treatment.
- May worsen heart failure or increase risk of certain cancers.
- Do not use with another TNF inhibitor or anakinra.
Pregnancy
May be used when clinically needed. It crosses the placenta less than many similar medicines; discuss treatment timing with a clinician.
Breastfeeding
Generally considered compatible because transfer into breast milk is expected to be low; consult a clinician.
Interactions
- Other biologic immune-suppressing medicines, including TNF inhibitors
- Anakinra or abatacept
- Live vaccines
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.