About Simvacor 20mg Tablets
HMG-CoA reductase inhibitor (statin)
Used for
- Lowers LDL cholesterol and triglycerides
- Reduces risk of heart attack and stroke in people at increased risk
Usual adult dose
Usually 10–40 mg once daily in the evening; dose depends on the condition and interacting medicines.
Usual dose in children
For familial hypercholesterolaemia, usually 10–40 mg once daily in the evening for ages 10–17; specialist supervision is needed.
Common side effects
- Muscle pain or weakness
- Headache
- Nausea or abdominal discomfort
- Raised liver enzymes
Important warnings
- Rarely causes serious muscle injury or liver problems.
- Risk of muscle injury increases with certain medicines and higher doses.
- Avoid during active liver disease.
- Seek prompt assessment for unexplained muscle pain, weakness, or dark urine.
Pregnancy
Not recommended during pregnancy; contact a healthcare professional if pregnancy occurs while taking it.
Breastfeeding
Breastfeeding is not recommended while taking simvastatin.
Interactions
- Grapefruit juice can increase simvastatin levels.
- Some antibiotics and antifungals can dangerously increase muscle side-effect risk.
- Interactions include ciclosporin, gemfibrozil, and some HIV or hepatitis medicines.
- Warfarin and other cholesterol medicines may require monitoring or dose changes.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.