About ticagrelor
Antiplatelet P2Y12 receptor blocker
Used for
- Reduces heart attack and stroke risk after acute coronary syndrome
- Helps prevent blood clots after coronary stent placement
Usual adult dose
Usually 90 mg twice daily during the first year after acute coronary syndrome; often reduced to 60 mg twice daily afterward. Take with low-dose aspirin unless directed otherwise.
Common side effects
- Bleeding
- Shortness of breath
- Bruising
- Slow or irregular heartbeat
Important warnings
- Can cause serious or fatal bleeding; avoid stopping without medical direction.
- Avoid with active bleeding or a history of bleeding inside the brain.
- Use cautiously with breathing problems, slow heartbeat, or severe liver disease.
- Tell clinicians before surgery or dental procedures.
Pregnancy
Human pregnancy data are limited; use only when expected benefits outweigh potential risks.
Breastfeeding
It is unknown whether ticagrelor passes into breast milk; discuss risks and alternatives with a clinician.
Interactions
- Aspirin doses above 100 mg daily may reduce effectiveness.
- Strong CYP3A inhibitors can raise levels and bleeding risk.
- Strong CYP3A inducers can reduce effectiveness.
- Other blood thinners and NSAIDs increase bleeding risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.