About naproxen
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Temporary relief of minor aches and pains, such as headache, muscle aches, and toothache
- Reduces fever
- Relieves menstrual cramps
- Relieves arthritis pain and inflammation
Usual adult dose
For over-the-counter pain or fever: 220 mg every 8–12 hours; first dose may be 440 mg. Maximum 660 mg in 24 hours.
Usual dose in children
Age 12 and older: use the adult over-the-counter dose. Not recommended under age 12 unless directed by a clinician.
Common side effects
- Heartburn or stomach pain
- Nausea
- Dizziness
- Fluid retention
Important warnings
- Can cause stomach ulcers, bleeding, or perforation, sometimes without warning.
- May increase risk of heart attack or stroke; risk can occur early and rise with prolonged use.
- Can worsen high blood pressure, heart failure, or kidney disease.
- Avoid combining with other NSAIDs; use caution with blood thinners or a history of ulcers.
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid from 30 weeks onward because of fetal risks.
Breastfeeding
Small amounts may enter milk; short-term use is generally considered compatible, but ask a healthcare professional for prolonged use.
Interactions
- Blood thinners and antiplatelet medicines may increase bleeding.
- Other NSAIDs, including ibuprofen, increase side effects.
- ACE inhibitors, ARBs, and diuretics may increase kidney risks or reduce blood-pressure control.
- Lithium or methotrexate levels may rise.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.