About sugammadex octasodium salt corresponds to sugammadex
Selective muscle-relaxant reversal agent
Used for
- Reverses rocuronium- or vecuronium-induced muscle relaxation after surgery.
Usual adult dose
Intravenous: usually 2 mg/kg for moderate block or 4 mg/kg for deep block; 16 mg/kg for immediate reversal in specific situations.
Usual dose in children
Evidence and approval vary; pediatric use is generally limited to reversing rocuronium-induced block in children aged 2 years or older.
Common side effects
- Nausea
- Vomiting
- Pain
- Slow heart rate
Important warnings
- Must be given intravenously by trained healthcare staff.
- Can cause severe allergic reactions and marked slowing of the heart.
- Hormonal contraceptives may be less effective for seven days; use additional non-hormonal contraception.
- May affect blood clotting, especially at higher doses or with anticoagulants.
Pregnancy
Human pregnancy information is limited; use only when a clinician considers it necessary.
Breastfeeding
It is unknown whether sugammadex enters breast milk; clinical advice is needed.
Interactions
- Hormonal contraceptives: reduced effectiveness; follow missed-dose precautions.
- Toremifene may prolong sugammadex exposure and delay recovery.
- Some medicines may increase recurrence of muscle relaxation; monitoring is required.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.