About normal human immunoglobulin
Human normal immunoglobulin (IVIG)
Used for
- Immune replacement for certain antibody deficiencies
- Treats immune thrombocytopenia
- Treats chronic inflammatory demyelinating polyneuropathy
- Treats other immune disorders, depending on the condition
Usual adult dose
Varies by condition: commonly 0.2–0.4 g/kg every 3–4 weeks for replacement; other conditions need different regimens.
Usual dose in children
For immune replacement, commonly 0.2–0.8 g/kg every 3–4 weeks; other uses have condition-specific regimens.
Common side effects
- Headache, fever, chills, or nausea
- Infusion reactions, including flushing or blood pressure changes
- Rare blood clots, kidney injury, or red blood cell breakdown
- Rare severe allergic reaction
Important warnings
- Infusion reactions are more likely with fast administration.
- Blood clots and kidney injury are serious risks, especially with risk factors.
- May interfere with some vaccine responses and antibody tests.
- Use and monitoring depend on the condition and product instructions.
Pregnancy
Use only when clinically needed; pregnancy experience is limited, and treatment should be monitored by a clinician.
Breastfeeding
Immunoglobulin is a normal component of breast milk; treatment is generally considered compatible with breastfeeding.
Interactions
- Live vaccines, such as measles or varicella vaccines, may be less effective for months.
- May interfere with laboratory tests involving antibodies.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.