About amoxicillin trihydrate potassium clavulanate
Penicillin antibiotic with beta-lactamase inhibitor
Used for
- Treats certain bacterial infections, including sinus, ear, chest, skin, and dental infections.
- Does not treat viral infections such as colds or flu.
Usual adult dose
Usually one tablet every 8 hours with food; dose and duration depend on infection and kidney function.
Usual dose in children
Children’s doses are based on weight and infection; this tablet is generally unsuitable for children under 40 kg.
Common side effects
- Diarrhoea, nausea, or vomiting
- Thrush
- Skin rash
- Rarely, severe allergic reaction or liver problems
Important warnings
- Avoid with a serious allergy to penicillin or related antibiotics.
- Seek urgent help for breathing difficulty, facial swelling, or a severe skin reaction.
- Can cause liver injury, especially with previous co-amoxiclav-related liver problems.
- Complete the prescribed course; unnecessary use promotes antibiotic resistance.
Pregnancy
Generally considered usable when prescribed; discuss risks and benefits with a healthcare professional.
Breastfeeding
Usually compatible; monitor the infant for diarrhoea, rash, or thrush.
Interactions
- Warfarin and other anticoagulants: may alter clotting tests.
- Methotrexate: may increase methotrexate effects or toxicity.
- Allopurinol: may increase the chance of skin rash.
- Probenecid: may increase amoxicillin levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.