About pentoxifylline
Xanthine derivative; blood-flow improving agent
Used for
- Helps relieve leg pain during walking caused by peripheral artery disease.
Usual adult dose
Usually 400 mg by mouth three times daily with meals; reduce to twice daily if poorly tolerated.
Common side effects
- Nausea or indigestion
- Dizziness or headache
- Flushing
- Increased bleeding or bruising
Important warnings
- Use caution with bleeding disorders or recent surgery.
- May increase bleeding risk, especially with blood thinners.
- Use caution with low blood pressure or severe kidney or liver disease.
- Swallow prolonged-release tablets whole; do not crush or chew.
Pregnancy
Use only when clearly needed; pregnancy safety information is limited.
Breastfeeding
Use caution; it is not known whether pentoxifylline passes into human milk.
Interactions
- Warfarin and other anticoagulants may increase bleeding.
- Antiplatelet medicines, such as aspirin, may increase bleeding.
- Blood-pressure medicines may increase dizziness or low blood pressure.
- Theophylline levels may rise when used together.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.