About itraconaz ole
Triazole antifungal
Used for
- Fungal infections of the skin and nails
- Certain serious fungal infections, including histoplasmosis and aspergillosis
Usual adult dose
Common regimens range from 100–400 mg daily, depending on infection and treatment duration.
Common side effects
- Nausea, stomach pain, or diarrhea
- Headache or dizziness
- Swelling or raised blood pressure
- Liver problems
Important warnings
- Can cause or worsen heart failure; avoid for nail infections with ventricular dysfunction.
- Rarely causes serious liver injury.
- Many medicines interact; some combinations can cause dangerous heart rhythm problems.
- Capsules need stomach acid for absorption; acid-reducing medicines can interfere.
Pregnancy
Avoid for nail infections during pregnancy; use for other infections only when a clinician judges benefits outweigh risks.
Breastfeeding
Small amounts may enter breast milk; discuss use with a healthcare professional.
Interactions
- Certain statins, sedatives, and heart-rhythm medicines may be unsafe with itraconazole.
- Rifampin, carbamazepine, and phenytoin can reduce itraconazole levels.
- Antacids and acid-reducing medicines can lower capsule absorption.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.