About clopidogrel
Antiplatelet medicine (P2Y12 inhibitor)
Used for
- Prevention of heart attack and stroke in people with vascular disease
- Prevention of blood clots after certain heart procedures, often with aspirin
Usual adult dose
Usually 75 mg once daily. For some heart conditions, treatment begins with a one-time loading dose.
Common side effects
- Bleeding or bruising more easily
- Nosebleeds
- Diarrhea or indigestion
- Rash
Important warnings
- Seek urgent care for severe, persistent, or unusual bleeding.
- Do not stop without medical guidance; stopping may increase clot risk.
- Tell clinicians before surgery or dental procedures.
- Rarely, can cause a serious blood disorder called thrombotic thrombocytopenic purpura.
Pregnancy
Use during pregnancy only when clearly needed; evidence is limited, and treatment depends on the condition.
Breastfeeding
It is unknown whether clopidogrel passes into human milk; discuss treatment with a clinician.
Interactions
- Aspirin and other blood thinners can increase bleeding risk.
- Ibuprofen and naproxen can increase bleeding risk.
- Omeprazole and esomeprazole may reduce clopidogrel's antiplatelet effect.
- Some antidepressants, including SSRIs, may increase bleeding risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.