About sugammadex as sugammadex sodium
Selective muscle relaxant reversal agent
Used for
- Reverses certain muscle-relaxing medicines used during general anaesthesia, especially rocuronium and vecuronium.
Usual adult dose
Usually 2 mg/kg intravenously for moderate block or 4 mg/kg for deep block; 16 mg/kg may be used for immediate reversal.
Usual dose in children
For children aged 2 years and older, usually 2 mg/kg intravenously for moderate block; use is limited to specific situations.
Common side effects
- Nausea
- Headache
- Pain or discomfort
- Slow heart rate, sometimes severe
Important warnings
- Must be given and monitored by trained anaesthesia professionals.
- Can cause serious allergic reactions or marked slowing of the heart.
- Dose depends on the muscle-relaxant blockade and body weight.
- May reduce hormonal contraceptive effectiveness for seven days.
Pregnancy
Human pregnancy information is limited; use only when a clinician considers it necessary.
Breastfeeding
It is unknown whether sugammadex passes into breast milk; discuss breastfeeding with a clinician.
Interactions
- Hormonal contraceptives: may reduce effectiveness; follow missed-dose precautions for seven days.
- Toremifene may delay sugammadex removal from the body.
- Some medicines may affect its ability to reverse muscle relaxation.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.