About norepinephrine bitartrate
Vasopressor; adrenergic agonist
Used for
- Raises blood pressure in severe acute low blood pressure, especially septic shock.
- Supports blood pressure during some other types of shock.
Usual adult dose
Continuous intravenous infusion, adjusted to blood pressure response; commonly starts at 0.05–0.1 micrograms/kg/min.
Usual dose in children
Continuous intravenous infusion in intensive care, adjusted to response; commonly starts at 0.05–0.1 micrograms/kg/min.
Common side effects
- High blood pressure
- Slow or irregular heartbeat
- Reduced blood flow to hands, feet, or organs
- Tissue injury if infusion leaks outside the vein
Important warnings
- Given by intravenous infusion with close monitoring, usually in hospital.
- Correct low blood volume when possible; the medicine can worsen poor circulation.
- Avoid leakage from the vein; severe tissue damage can occur.
- Do not stop suddenly; blood pressure may fall.
Pregnancy
Use when needed for serious low blood pressure; reduced blood flow to the uterus may affect the fetus.
Breastfeeding
Breastfeeding safety information is limited; use is generally restricted to monitored emergency treatment.
Interactions
- Some antidepressants, including MAO inhibitors and tricyclics, can intensify blood pressure effects.
- Certain anesthetics and other medicines that raise blood pressure can increase heart rhythm risks.
- Medicines that slow the heart may increase the risk of a very slow heartbeat.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.