About Atogepant Monohydrate 60.0 mg/ Tab. 9.20 w/w
CGRP receptor antagonist; migraine preventive
Used for
- Prevention of episodic migraine in adults.
- Prevention of chronic migraine in adults.
Usual adult dose
Usually 60 mg by mouth once daily; some conditions or interacting medicines require a lower dose.
Common side effects
- Nausea
- Constipation
- Fatigue or sleepiness
- Decreased appetite or weight
Important warnings
- May cause serious allergic reactions, including swelling or difficulty breathing.
- Constipation can be severe; rare cases required hospital treatment.
- May cause high blood pressure or worsening of existing high blood pressure.
- May cause Raynaud phenomenon, with cold, numb, or painful fingers or toes.
Pregnancy
Human pregnancy data are limited; use during pregnancy is generally avoided unless a clinician considers it necessary.
Breastfeeding
It is unknown whether atogepant passes into human milk; discuss potential risks with a clinician.
Interactions
- Strong CYP3A4 inhibitors can increase atogepant levels; dose adjustment is needed.
- Strong CYP3A4 inducers can reduce effectiveness; avoid where possible.
- OATP inhibitors can increase levels and may require dose adjustment.
- Dose adjustments may be needed with certain medicines affecting kidney or liver function.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.