About INSULIN GLARGINE 100U/ML + LIXISENATIDE 50MCG/ML
Basal insulin and GLP-1 receptor agonist combination
Used for
- Improves blood sugar control in adults with type 2 diabetes, alongside diet and exercise.
Usual adult dose
Injected under the skin once daily within the hour before the first meal. Starting and adjustment doses depend on prior treatment and blood sugar.
Common side effects
- Low blood sugar
- Nausea, vomiting, or diarrhea
- Injection-site reactions
- Headache
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Can cause severe low blood sugar; risk increases with some diabetes medicines.
- Not for treating sudden high blood sugar; use a separate rapid-acting insulin if prescribed.
- May cause pancreatitis or worsening stomach-emptying problems.
Pregnancy
Insulin is commonly used in pregnancy, but this combination has limited pregnancy data. Treatment may need changing under medical supervision.
Breastfeeding
Insulin glargine is compatible with breastfeeding; lixisenatide data are limited. Monitor treatment and infant feeding with a clinician.
Interactions
- Other diabetes medicines, especially sulfonylureas, can increase low blood sugar risk.
- Beta blockers may mask warning signs of low blood sugar.
- Slows stomach emptying and can affect absorption of oral medicines.
- Do not combine with another lixisenatide or GLP-1 medicine.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.