About amiloride hcl + hydrochlorothiazide
Potassium-sparing and thiazide diuretic combination
Used for
- High blood pressure
- Fluid retention caused by heart, liver, or kidney conditions
Usual adult dose
Usually one tablet once daily; the dose may be adjusted according to response and potassium levels.
Common side effects
- Dizziness or headache
- Nausea or stomach upset
- Muscle cramps or weakness
- Changes in potassium or sodium levels
Important warnings
- May cause dangerously high potassium, especially with kidney disease.
- Regular kidney function and electrolyte tests are important.
- Avoid potassium supplements and potassium-containing salt substitutes unless prescribed.
- May cause dehydration, low blood pressure, or worsening kidney function.
Pregnancy
Use only when clearly needed; hydrochlorothiazide is generally avoided for routine high blood pressure treatment during pregnancy.
Breastfeeding
Hydrochlorothiazide may reduce milk supply, particularly at higher doses; seek clinical guidance about use.
Interactions
- ACE inhibitors, ARBs, or aliskiren can increase potassium.
- Potassium supplements and salt substitutes can cause high potassium.
- NSAIDs may reduce the diuretic effect and worsen kidney function.
- Lithium levels may rise and become toxic.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.