About piroxicam
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Short-term relief of pain and inflammation from rheumatoid arthritis or osteoarthritis.
- Short-term treatment of acute musculoskeletal pain.
Usual adult dose
Usually 20 mg intramuscularly once daily; use the shortest possible duration, generally no more than two days.
Common side effects
- Stomach pain, indigestion, nausea, or diarrhea.
- Injection-site pain or irritation.
- Dizziness or headache.
- Swelling or increased blood pressure.
Important warnings
- Can cause stomach ulcers, bleeding, or perforation; risk increases with age and longer treatment.
- May increase risk of heart attack or stroke, especially with prolonged use.
- Avoid with aspirin or other NSAIDs; contraindicated around coronary artery bypass surgery.
- Avoid in severe kidney, liver, or heart failure, and with NSAID allergy.
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid from 30 weeks because of fetal heart and labor risks.
Breastfeeding
Use is generally not recommended because piroxicam persists in the body and may expose the infant.
Interactions
- Warfarin and other blood thinners can increase bleeding.
- Aspirin and other NSAIDs increase stomach and bleeding risks.
- ACE inhibitors, ARBs, and diuretics may worsen kidney function.
- Lithium or methotrexate levels may increase.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.