About Melorem 7.5mg Tablets
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Relief of pain and inflammation in osteoarthritis
- Relief of pain and inflammation in rheumatoid arthritis
Usual adult dose
Osteoarthritis: 7.5 mg once daily; may increase to 15 mg daily. Rheumatoid arthritis: 15 mg once daily; some patients use 7.5 mg daily.
Usual dose in children
For juvenile rheumatoid arthritis in children aged 2 years and older: 0.125 mg/kg once daily, maximum 7.5 mg daily; specialist supervision is needed.
Common side effects
- Indigestion, nausea, or abdominal pain
- Diarrhoea or constipation
- Headache or dizziness
- Fluid retention and raised blood pressure
Important warnings
- May cause stomach ulcers, bleeding, or perforation
- Can increase heart attack and stroke risk
- May impair kidney function, especially with dehydration
- Avoid with other NSAIDs; use the lowest effective dose briefly
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid from 30 weeks because of fetal risks.
Breastfeeding
Small amounts may pass into breast milk; alternatives are generally preferred, especially for newborn or premature infants.
Interactions
- Blood thinners, antiplatelets, or corticosteroids increase bleeding risk
- Other NSAIDs increase stomach and kidney harms
- ACE inhibitors, ARBs, or diuretics may worsen kidney function
- Lithium or methotrexate levels may increase
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.